中华皮肤科杂志 ›› 2002, Vol. 35 ›› Issue (5): 364-365.

• 论著 • 上一篇    下一篇

小范围发生皮肤诺卡菌病23例

温海, 陈江汉, 徐红, 姚志荣, 吴建华, 陈裕充, 朱红梅, 赵瑾   

  1. 上海长征医院皮肤科, 200003
  • 收稿日期:2001-12-25 出版日期:2002-10-15 发布日期:2002-10-15

Primary Cutaneous Nocardiosis Associated with Intramuscular Injection

WEN Hai, CHEN Jianghan, XU Hong, YAO Zhirong, WU Jianhua, CHEN Yuchong, ZHU Hongmei, ZHAO Jin   

  1. Department of Dermatology, Changzheng Hospital, Shanghai 200003, China
  • Received:2001-12-25 Online:2002-10-15 Published:2002-10-15

摘要: 目的 报道国内首见群体发生的皮肤诺卡菌病23例。方法 详细检查了23例患者的皮疹表现,对6例患者的标本进行了病原学鉴定,同时对可能的发病原因进行了调查。结果 发现全部患者同住一个自然村,发病均与臀部肌内注射有关,每例患者均于肌内注射治疗后2-10个月内出现臀部(肌肉注射部位)结节、脓肿,部分皮损破溃成溃疡及窦道,病原学检查证实为星形奴卡菌。结论 23例皮肤奴卡菌病的发生均与肌内注射有关。

关键词: 诺卡氏菌,星状, 诺卡氏菌感染

Abstract: Objective To investigate and report a group of patients with cutaneous nocardiosis occurring in China.Methods The skin lesion of twenty-three patients were examined and the pathogen was identified.The possible cause of this disease was also investigated.Results All the twenty-three patients belong to a same village in a province.Skin lesions on buttocks manifested as nodules and abscesses whereas some other lesions as ulcers and draining sinuses,occurring 2-10mo nths after intramuscular injection.The pathogens were identified as Nocardia asteroides.Conclusion Twenty-three patients of cutaneous nocardiosis were related to intramu scular injection.

Key words: Nocardial infections, Nocardia asteroides