中华皮肤科杂志 ›› 2003, Vol. 36 ›› Issue (8): 441-442.

• 论著 • 上一篇    下一篇

31例深部真菌病临床和尸检分析

郝飞, 阎衡, 叶庆佾   

  1. 第三军医大学西南医院皮肤性病科 重庆 400038
  • 收稿日期:2002-08-16 出版日期:2003-08-15 发布日期:2003-08-15

Clinical and Autopsy Analysis of Systemic Fungal Diseases:A Report of 31 Cases

HAO Fei, YAN Heng, YE Qing-yi   

  1. Department of Dermatology and Venereology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
  • Received:2002-08-16 Online:2003-08-15 Published:2003-08-15

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摘要： 目的 了解尸解患者中真菌感染状况及其与临床的关系。方法 非选择性总结30年来本院成人(年龄≥16岁)尸检资料,依据病理切片真菌形态确定真菌感染的存在,并进行临床和病理对照分析。结果 396例尸检中发生真菌感染31例(7.8%),其中曲霉感染17例,占全部真菌感染的54.8%。真菌感染受累脏器频率高低依次为肺(83.87%)、肾(48.39%)、脑(35.48%)和心脏(29.03%),其中21例成为直接致死的原因。结论 深部真菌感染是危重患者死亡的重要原因之一,曲霉已成为尸检病例中深部真菌感染主要的致死真菌。

关键词: 真菌病, 尸体解剖

Abstract: Objective To investigate the prevalence of systemic fungal infection in patients at autopsy and its association with clinical data.Methods The materials from unselected adult patients were examined at necropsy in our hospital from 1971 to 2000,and the fungal species were identified by their morphologies in pathology.The clinical and pathological data were compared.Results The rate of fungal infection was 7.8%(31/396) among 396 cases.Seventeen(54.8%) of the 31 cases were infected with aspergillus.The frequencies of organs involved with fungal infection were 83.87% in lungs,48.39% in kidneys,35.48% in brain and 29.03% in heart,respectively.The fungal infection attributed directly to death in 21 cases.Conclusion Systemic fungal infection is one of the most common fatal causes among the critically ill patients,and aspergillosis becomes a major pathogenic fungus for patients with systemic fungal infection at autopsy.

Key words: Mycoses, Autopsy