光接触过敏原与黄褐斑的相关性研究

中华皮肤科杂志 ›› 2011, Vol. 44 ›› Issue (7): 511-512.

光接触过敏原与黄褐斑的相关性研究

刘至昱¹,傅雯雯²,胡跃³,徐昱³

1. 同济大学附属第十人民医院
2. 上海复旦大学附属华山医院皮肤科
3. 上海医科大学附属华山医院皮肤科

收稿日期:2010-08-23 修回日期:2011-02-22 出版日期:2011-07-15 发布日期:2011-07-12
通讯作者: 傅雯雯 E-mail:fuww@medmail.com.cn

Relationship between photoallergens and melasma

Received:2010-08-23 Revised:2011-02-22 Online:2011-07-15 Published:2011-07-12

摘要/Abstract

摘要：

目的探讨常见光接触过敏原与黄褐斑之间的相关性。方法依循英国光学皮肤病研究组推荐的光斑贴试验操作步骤，从国家化妆品光感性皮炎诊断标准（GB17149.6-1997）、国家化妆品接触性皮炎诊断标准（GB17149.2-1997）及国家职业性皮肤病诊断标准（GBZ18-2002）中筛选出20种常见过敏原。对50例黄褐斑患者及30例正常人对照进行光斑贴试验。结果 50例黄褐斑患者中光斑贴试验阳性24例占48.0%，30例正常人对照中光斑贴试验阳性7例占23.33%，黄褐斑患者光斑贴阳性率显著高于对照组（P < 0.05）。结论黄褐斑患者光斑贴试验阳性率高于正常人。

关键词: 斑片试验

Abstract:

Objective To study the relationship between common photoallergens and melasma. Methods Twenty allergens were selected according to the National Diagnostic Criteria for Photosensitive Dermatitis induced by cosmetics, National Diagnostic Criteria for Contact Dermatitis induced by cosmetics and National Diagnostic Criteria for Occupational Skin Diseases. Based on the standard procedures for photopatch test recommended by the British Photodermatology Group （BPG）, photopatch test was performed on 50 patients with melasma and 30 normal controls. Results The positivity rate of photopatch test was 48.0% （24/50） in patients suffering from melasma, significantly higher than in the controls［23.33% （7/30）, P < 0.05］. Conclusion Patients with melasma appear more likely to have positive photopatch test than normal controls.

Key words: Patchtests

刘至昱傅雯雯胡跃徐昱. 光接触过敏原与黄褐斑的相关性研究[J]. 中华皮肤科杂志, 2011, 44(7): 511-512.

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