中华皮肤科杂志 ›› 2011, Vol. 44 ›› Issue (5): 356-357.

• 研究报道 • 上一篇    下一篇

女性尖锐湿疣患者宫颈亚临床感染与复发关系的研究

栾红1,姜丽亚2,孟宪敏3   

  1. 1. 聊城人民医院
    2. 济南山东大学临床医学院济南市中心医院皮肤科
    3. 山东省聊城市人民医院皮肤科
  • 收稿日期:2010-12-07 修回日期:2011-01-06 出版日期:2011-05-15 发布日期:2011-05-03
  • 通讯作者: 栾红 E-mail:guochunxiao1020@163.com

Relationship between subclinical cervical human papillomavirus （HPV） infection and recurrence of condyloma acuminatum in patients

  • Received:2010-12-07 Revised:2011-01-06 Online:2011-05-15 Published:2011-05-03

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摘要：

目的 探讨女性尖锐湿疣（CA）患者宫颈中人乳头瘤病毒（HPV）亚临床感染与CA复发的关系。方法 根据临床及病理结果，收集107例女性CA患者及65例正常女性患者的宫颈拭子，将其分为高复发组（52例）、低复发组（55例）和正常对照组（65例），利用基因芯片技术检测患者宫颈中是否存在HPV病毒及其亚型，并进行统计学分析。结果 高复发组中67.3％（35/52）例检测出HPV病毒，低复发组中34.5％（19/55）检测出HPV病毒，正常对照组4.6％（3/65）检测出HPV病毒，各组间差异有统计学意义。结论 女性CA患者宫颈中存在HPV病毒感染的潜在病灶可能是CA复发的原因之一。

关键词: 关键词 人乳头瘤病毒 尖锐湿疣 复发

Abstract:

Objective To investigate the relationship between subclinical cervical HPV infection and recurrence of condyloma acuminatum （CA） in patients. Methods Cervical swabs were collected from 52 patients with frequently recurrent CA, 55 patients with infrequently recurrent CA, and 65 normal human controls. The Genechip method was performed to detect the presence and type of HPV in cervical swabs followed by a statistical analysis. Results HPV was found in 67.3% （35/52） of swabs from patients with frequently recurrent CA, 5% （19/55） from patients with infrequently recurrent CA, and 4.6% （3/65） in the controls. There was a statistical difference among the three groups in the detection rate of HPV. Conclusion The subclinical cervical HPV infection may contribute to the recurrence of CA.