中华皮肤科杂志 ›› 2011, Vol. 44 ›› Issue (1): 47-49.

• 论著 • 上一篇    下一篇

慢性荨麻疹患者生活质量评估及皮肤病生活质量指数的因子分析和信度分析

刘江波1,司爱丽2,邓蕾2,赖晓娟2   

  1. 1. 惠州市惠阳区人民医院
    2.
  • 收稿日期:2010-06-18 修回日期:2010-07-13 出版日期:2011-01-15 发布日期:2011-01-10
  • 通讯作者: 刘江波 E-mail:liujiangbo126@126.com

Assessment of quality of life in patients with chronic urticaria and reliability of the Dermatology Life Quality Index （DLQI）

  • Received:2010-06-18 Revised:2010-07-13 Online:2011-01-15 Published:2011-01-10

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摘要：

目的 探讨慢性荨麻疹（CU）对患者生活质量的影响，分析皮肤病生活质量指数（DLQI）在评估CU患者生活质量时的因子结构及信度。方法 用DLQI测量CU患者的生活质量，用因子分析及信度分析评估DLQI的因子结构及信度。结果 调查85例门诊就诊的慢性荨麻疹患者，13例因合并其他疾病或未完全回答DLQI的问题而被剔除。72例CU患者年龄（33.43 ± 0.90）岁，病程中位数6个月。DLQI评分为1 ~ 23，平均9.46 ± 0.61，DLQI评分与患者的年龄、性别、病程间相关性无统计学意义。CU对生活质量影响最显著的是症状与感受（50%），其次为工作和学习（40.67%）。因子分析显示，DLQI量表用于测评CU时，特征值 > 1的因子有2个。信度分析显示F = 31.88（P < 0.01），Hotelling T2检验，F = 29.87（P < 0.01），整体量表Cronbach α = 0.836，删除问题1，α达最大值0.849。结论 CU对患者的生活质量有中等程度的影响。DLQI可以用来测评CU患者的生活质量，结果的可信度较高。

关键词: 信度分析

Abstract:

Objective To evaluate the influence of chronic urticaria on the quality of life in patients by the DLQI, and to assess the factor structure and reliability of the DLQI. Methods The DLQI （Chinese version） was used to evaluate the quality of life of outpatients with CU. The reliability and factor structure of the DLQI were evaluated by reliability analysis and factor analysis. Results Eighty-five patients were asked to complete the DLQI and 13 patients were excluded for other complicated disorders or unanswered items in the DLQI. The mean age was 33.43 ± 0.90 years in the 72 patients with a median clinical course of 6 months. The DLQI score, which varied from 1 to 23 with an average of 9.46 ± 0.61, was uncorrelated to the patients' age, sex, or clinical course of CU （all P > 0.05）. The impact of CU was observed mainly on the "synptoms and feeling" （50%）, followed by "work and study" （40.67%）. Factor analysis indicated that there were two dimensions with eigenvalues greater than 1.0, accounting for 53.7% of the variances. Reliability analysis showed that the Cronbach's α value was 0.836, and reached 0.849 if the item 1 in the DLQI was deleted. An analysis of variance showed that the F value was 31.88 （P < 0.01）, and Hotelling T2 test yielded an F value of 29.87（P < 0.01）. Conclusions CU has a moderate impact on the quality of life in patients. DLQI can be applied to the evaluation of quality of life in patients with CU with a high reliability, but more attention should be paid to the interference from item 1 to the reliability of the assessment.

Key words: Reliability analysis