中华皮肤科杂志 ›› 2011, Vol. 44 ›› Issue (1): 52-54.

• 短篇论著 • 上一篇    下一篇

白癜风进展相关危险因素分析

卢良君1,许爱娥2,关翠萍3,陈梅花4   

  1. 1. 杭州市第三人民医院皮肤科
    2. 安徽医科大学附属杭州市第三人民医院皮肤科
    3. 杭州市第三人民医院
    4. 武汉市第一人民医院皮肤科
  • 收稿日期:2010-03-02 修回日期:2010-07-27 出版日期:2011-01-15 发布日期:2011-01-10
  • 通讯作者: 许爱娥 E-mail:xuaiehz@msn.com

Risk factors associated with the progression of vitiligo

  • Received:2010-03-02 Revised:2010-07-27 Online:2011-01-15 Published:2011-01-10

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摘要：

目的 探讨白癜风进展相关的可能危险因素。方法 采用问卷调查方式获得1088例白癜风患者的临床资料，对同病程白癜风患者进展的可能诱因与皮损面积的相关性进行统计分析，有无诱因的二组间患者的比较采用平均受累面积指数的配对t检验。结果 有家族史与无家族史患者组间平均受累面积指数差异无统计学意义（t = 1.499，P > 0.05）；有同形反应与无同形反应患者组的平均受累面积指数差异有统计学意义（t = 6.770，P < 0.01），且有同形反应患者组平均受累面积指数更高；伴精神因素与无精神因素影响的患者组间平均受累面积指数差异有统计学意义（t = 6.704，P < 0.01）。结论 有精神因素影响或同形反应的患者白斑进展较快。

关键词: 危险因素

Abstract:

Objective To analyse the possible risk factors associated with the progression of vitiligo. Methods A questionnaire survey was carried out to collect the clinical data on 1088 patients with vitiligo. The relationship between possible inducements to the progression of vitiligo and lesion area was statistically analyzed in patients with the same clinical course of vitiligo. Paired t test was performed to compare the mean area index of involvement between patients with inducements and those without. Results A significant difference was observed in the mean area index of involvement between patients with isomorphic response and those without （t = 6.770, P < 0.01） as well as between patients negatively affected by psychiatric factors and those unaffected （t = 6.704, P < 0.01）, but not between patients with family history and those without （t = 1.499, P > 0.05）. Conclusion A rapid progression of vitiligo is more likely to be observed in patients negatively affected by psychiatric factors and patients with isomorphic response.