中华皮肤科杂志 ›› 2010, Vol. 43 ›› Issue (7): 512-513.

• 病例报告 • 上一篇    下一篇

纤维肉瘤型隆突性皮肤纤维肉瘤一例

温蓬飞1,王琳2   

  1. 1. 四川省成都市四川大学华西医院皮肤性病科
    2. 成都市四川大学华西医院皮肤科
  • 收稿日期:2009-12-16 修回日期:2010-02-07 出版日期:2010-07-15 发布日期:2010-07-13
  • 通讯作者: 温蓬飞 E-mail:pfw728@126.com

A case of fibrosacomatous dermatofibrosarcoma protuberans

2   

  • Received:2009-12-16 Revised:2010-02-07 Online:2010-07-15 Published:2010-07-13

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摘要：

摘要] 报告1例纤维肉瘤型隆突性皮肤纤维肉瘤(DFSP-FS)。患者女，36岁。背部反复丘疹、结节12年。曾经2次手术切除。组织病理检查示瘤细胞排列呈涡纹状，形态较一致，呈梭形，部分区域内瘤细胞排列成鱼骨状，异型性及分裂相均较前者为高。免疫组化检查示涡纹状结构区域内瘤细胞CD34弥漫强阳性，鱼骨状区域仅个别细胞CD34表达阳性。诊断：纤维肉瘤型隆突性皮肤纤维肉瘤。行广泛切除术，术后9个月，未见复发。

关键词: [关键词] 隆突性皮肤纤维肉瘤，纤维肉瘤样变

Abstract:

[Abstract] A case of fibrosacomatous dermatofibrosarcoma protuberans(DFSP-FS) is reported. A 36-year-old female presented with nodules on her back for twelve years. She had experienced two recurrences of the tumor following local excisions. Histopathologically, most of the tumor cells were uniform in spindle shape and arranged in a storiform growth pattern. While in a focal area, some tumor cells were more atypical and more frequent mitoses which arranged in a herringbone pattern. Immunohistochemically, the tumor cells were strongly positive for CD34 in the storiform-patterned area while only a few tumor cells were positive for this marker in the herringbone-patterned area respectively. The diagnosis of fibrosacomatous dermatofibrosarcoma protuberans was made. Wide local excision was performed and the patient continues to be free of tumor at nine months from resection.

Key words: [Keywords] dermatofibrosarcoma protuberans, fibrosarcomatous change