中华皮肤科杂志 ›› 2008, Vol. 41 ›› Issue (7): 462-464.

• 论著 • 上一篇    下一篇

长脉冲半导体激光脱毛的长期疗效和安全性评价

冯雨苗 周展超 吴秋菊 吴余乐 燕淑美 戎慧珍 贾高蓉 厉建鸣   

  1. 中国医学科学院皮肤病研究所 南京医科院皮研所 南京 医科院皮研所 南京医科院皮研所 南京医科院皮研所 南京医科院皮研所
  • 收稿日期:2007-10-31 修回日期:2008-03-27 发布日期:2008-07-15
  • 通讯作者: 冯雨苗 E-mail:feng.yumiao@yahoo.com.cn

Evaluation of the long-term therapeutic effects and safety of diode laser in hair removal

FENG Yu-Miao WU Qiu-ju   

  • Received:2007-10-31 Revised:2008-03-27 Published:2008-07-15
  • Contact: FENG Yu-Miao E-mail:feng.yumiao@yahoo.com.cn

摘要: 目的 评价长脉冲半导体激光对于Ⅲ-Ⅴ型皮肤多毛患者脱毛的长期疗效和安全性。方法 用长脉宽半导体激光(波长800 nm,脉宽30 ms,光斑大小9 mm × 9 mm)对350例多毛患者进行多次治疗。治疗结束后22.5个月,回顾性分析了脱毛的疗效和不良反应,每个部位根据治疗次数分2组: < 6次组和≥6次组(腋窝分为 < 4次组和≥4次组),比较不同部位这2组脱毛的疗效。结果 随访到并进行评价的多毛患者235例共375处部位。经2 ~ 18次脱毛治疗后,有效302处,总有效率为80.53%。不同部位2个治疗次数组疗效有一定差异,唇部≥6次组治疗部位38处,有效33处,有效率86.84%, < 6次组治疗部位20处,有效7处,有效率35.00%;面颈(唇以外)≥6次组治疗部位38处,有效26处,有效率68.42%, < 6次组治疗部位13处,有效4处,有效率30.77%;下肢≥6次组治疗部位50处,有效46处,有效率92.00%, < 6次组治疗部位9处,有效5处;躯干≥6次组治疗部位23处,有效20处,有效率86.96%, < 6次组治疗部位8处,有效4处;以上各部位≥6次组疗效均优于 < 6次组(P < 0.05)。腋窝≥4次组治疗部位97处,有效91处,有效率93.81%, < 4次组治疗部位9处,有效5处,两组疗效比较,P < 0.01。上肢部两组疗效比较,差异无统计学意义(P > 0.05)。235例患者中有6例出现不良反应,包括色素沉着、毛囊性丘疹、瘙痒、水疱、白色毛发,未见色素减退及瘢痕形成。结论 长脉冲半导体激光对Ⅲ-Ⅴ型皮肤多毛患者脱毛安全有效。疗效与脱毛部位、治疗次数相关。

关键词: 脱毛, 半导体激光

Abstract: Objective To evaluate the long-term effects and safety of diode laser in hair removal. Methods A retrospective study was conducted. In this study, 350 patients with hypertrichosis were treated by an 800-nm diode laser with a pulse duration of 30 ms for various sessions. Two groups were divided based on the treatment sessions: group A receiving 6 (≥4 for axillae) or more treatments, group B less than 6 (< 4 for axillae) treatments. Patients were followed up for 8 months to 3 years (mean 22.5 months) by return visit or telephone. Evaluation of efficacy and side effects were performed. Results Follow-up and evaluation were completed in 235 patients, and a total of 375 sites treated. After 2-18 treatments, a total effective rate of 80.53% (302/375) was achieved. Significant higher effective rates were observed in group B compared with group A at all sites 86.84% (33/38) vs 35.00% (7/20) on the lips, 68.42% (26/38) vs 30.77% (4/13) on the face and neck, 92.00% (46/50) vs 55.56% (5/9) in lower extremities, 86.96% (20/23) vs 50.00% (4/5) on the trunk, 93.81% (91/97) vs 55.56% (5/9) at the axillae, 92.16% (47/51) vs 73.68% (14/19) in the upper extremities (all P < 0.05). Side effects were noted in only 6 cases, including hyperpigmentation, itching, and development of follicular papules, blisters and white hair. Neither hypopigmentation nor scarring was observed. Conclusions Diode laser system is effective and safe for hair removal. The effect varies with lesional sites and treatment sessions.

Key words: Hair removal, Diode laser