Sweet综合征合并SAPHO综合征1例

doi:10.35541/cjd.20210078

中华皮肤科杂志 ›› 2023, Vol. 56 ›› Issue (5): 447-448.doi: 10.35541/cjd.20210078

Sweet综合征合并SAPHO综合征1例

张欣璐¹ 吴遐² 向奕蓉¹ 邵禹铭¹ 张文³ 张上珠³

¹中国医学科学院北京协和医学院临床学院，北京 100730；²中国医学科学院北京协和医学院北京协和医院内科，北京 100730；³中国医学科学院北京协和医学院北京协和医院风湿免疫科风湿免疫病学教育部重点实验室国家皮肤与免疫疾病临床医学研究中心，北京 100730

收稿日期:2021-01-26 修回日期:2021-10-22 发布日期:2023-05-04
通讯作者: 张上珠 E-mail:irenezhangpumch@163.com

A case of Sweet syndrome complicated by SAPHO syndrome

Zhang Xinlu¹, Wu Xia², Xiang Yirong¹, Shao Yuming¹, Zhang Wen³, Zhang Shangzhu³

¹School of Clinical Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China; ²Department of Internal Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China; ³Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing 100730, China

Received:2021-01-26 Revised:2021-10-22 Published:2023-05-04
Contact: Zhang Shangzhu E-mail:irenezhangpumch@163.com

摘要/Abstract

摘要： 患者女，48岁，因右小腿间歇疼痛、肿胀10年就诊。2010年患者无明显诱因下出现右小腿疼痛、肿胀，间断外用蒙药贴剂（具体不详）治疗，右小腿疼痛、肿胀反复出现。2018年8月无诱因下出现发热，体温最高38.5 ℃，伴头痛、乏力，3 d后右下眼睑出现数个米粒大小红色丘疹，逐渐扩大融合至硬币大小，形成痛性水肿性红斑，中央有水疱（图1A），伴压痛，无渗出……

张欣璐吴遐向奕蓉邵禹铭张文张上珠. Sweet综合征合并SAPHO综合征1例[J]. 中华皮肤科杂志, 2023,56(5):447-448. doi:10.35541/cjd.20210078

Zhang Xinlu, Wu Xia, Xiang Yirong, Shao Yuming, Zhang Wen, Zhang Shangzhu. A case of Sweet syndrome complicated by SAPHO syndrome[J]. Chinese Journal of Dermatology, 2023, 56(5): 447-448.doi:10.35541/cjd.20210078

参考文献 5

［1］	Kahn MF, Khan MA. The SAPHO syndrome［J］. Baillieres Clin Rheumatol, 1994,8（2）:333⁃362. doi: 10.1016/s0950⁃3579（94）80022⁃7.
［2］	Beretta⁃Piccoli BC, Sauvain MJ, Gal I, et al. Synovitis, acne, pustulosis, hyperostosis, osteitis （SAPHO） syndrome in childhood: a report of ten cases and review of the literature［J］. Eur J Pediatr, 2000,159（8）:594⁃601. doi: 10.1007/s00431000 0500.
［3］	Beretta⁃Piccoli BC, Sauvain MJ, Gal I, et al. Synovitis, acne, pustulosis, hyperostosis, osteitis （SAPHO） syndrome in childhood: a report of ten cases and review of the literature［J］. Eur J Pediatr, 2000,159（8）:594⁃601. doi: 10.1007/s004310000500.
［4］	Tlougan BE, Podjasek JO, O′Haver J, et al. Chronic recurrent multifocal osteomyelitis （CRMO） and synovitis, acne, pustulosis, hyperostosis, and osteitis （SAPHO） syndrome with associated neutrophilic dermatoses: a report of seven cases and review of the literature［J］. Pediatr Dermatol, 2009,26（5）:497⁃505. doi: 10. 1111/j.1525⁃1470.2009.00984.x.
［5］	Bachmeyer C, Begon E, Blum L, et al. Overlapping neutrophilic dermatosis in a patient with SAPHO syndrome［J］. Arch Dermatol, 2007,143（2）:275⁃276. doi: 10.1001/archderm.143.2.275.

Sweet综合征合并SAPHO综合征1例

A case of Sweet syndrome complicated by SAPHO syndrome

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