中华皮肤科杂志

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30例神经梅毒的临床特征

周畅, 丰岩清, 张成   

  1. 中山大学附属第一医院神经内科, 广州510080
  • 收稿日期:2006-07-17 出版日期:2007-05-15 发布日期:2007-05-15
  • 通讯作者: 张成,email:czym@gzsums.edu.cn E-mail:czym@gzsums.edu.cn

Clinical features of 30 cases of neurosyphilis

ZHOU Chang, FENG Yan-qing, ZHANG Cheng   

  1. Departmerit of Neurology, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China
  • Received:2006-07-17 Online:2007-05-15 Published:2007-05-15

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摘要： 目的 分析神经梅毒的临床特征。方法 回顾分析我院30例神经梅毒患者的年龄、性别、临床表现、脑脊液改变和神经影像学检查等资料。结果 30例患者符合神经梅毒的诊断。最常见的临床类型为脑膜血管型梅毒占37%,其次为脊髓痨占20%、麻痹性痴呆占20%。平均发病年龄是50.8岁,除了1例为女性外,均为男性。常见的症状是脑卒中,占37%,常见的体征是腱反射减弱、痴呆和深感觉障碍,分别占30%。结论 神经梅毒的临床表现复杂多样,临床上应高度警惕。

关键词: 神经梅毒, 临床特征, 脑血管意外

Abstract: Objective To assess the clinical features of neurosyphilis(NS).Methods A retro-spective study was performed on the age,gender,clinical manifestations,changes in cerebrospinal fluid,and neuroimaging findings of 30 patients diagnosed as NS in our hospital.Results The most common clinical type was meningovascular syphilis(37%),followed by tabes dorsalis(20%)and general paresis(20%). Patients were all males except one female,with a mean onset age of 50.8 years.The most common symptom was stroke(37%),and the most frequent signs included tendon hyporeflexia(30%),dementia(30%), abnormalities in deep sensation(30%).Conclusions Neurosyphilis has diverse clinical presentations,and clinicians should pay much attention to it.

Key words: Neurosyphilis, Clinical features, Cerebrovascular accident