中华皮肤科杂志 ›› 2007, Vol. 40 ›› Issue (2): 83-85.

• 论著 • 上一篇    下一篇

口服盐酸莫西沙星治疗非淋菌性尿道(宫颈)炎临床观察

全国多中心临床观察组   

  1. 全国多中心临床观察组
  • 收稿日期:2006-09-11 发布日期:2007-02-15
  • 通讯作者: 傅志宜,mail:fuzhiyi@medmail．com．cn E-mail:fuzhiyi@medmail．com．cn

Clinical efficacy of moxifloxacin for the treatment of nongonococcal urethritis/cervicitis

  1. National Multiple-Center Clinical Study Group
  • Received:2006-09-11 Published:2007-02-15

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摘要： 目的 观察口服盐酸莫西沙星治疗非淋菌性尿道(宫颈)炎的临床疗效和安全性.方法 沙眼衣原体或/和解脲脲原体感染引起的非淋菌性尿道(宫颈)炎患者504例,采用盐酸莫西沙星口服,每次400 mg,每日1次,连续12天.结果 504例患者痊愈率为68.4%,总有效率为83.1%.沙眼衣原体和解脲脲原体感染清除率分别为84.8%和87.2%.不良反应发生率为7.9%.结论 盐酸莫西沙星治疗非淋菌性尿道(宫颈)炎疗效好,安全性高.

关键词: 衣原体, 沙眼, 解脲支原体, 尿道炎, 宫颈炎, 莫西沙星

Abstract: Objective To evaluate the safety and efficacy of moxifloxacin in the treatment of nongonococcal urethritis/cervicitis.Methods A total of 504 patients with nongonococcal urethritis/cervicitis due to Chlamydia trachomatis (CT) or/and Ureaplasma urealyticum (UU) infection were enrolled.All patients were treated with oral moxifloxacin 400 rag daily for 12 days.Results The overall cure rate and response rate were 68.4% and 83.1%,respectively.The clearance rates of CT and UU were 84.8% and 87.2%,respectively.Moxifloxacin was well tolerated.The incidence of adverse events was 7.9%,and all adverse events were mild and reversible.Conclusion Moxifloxacin has high efficacy and safety in treating nongonococcal urethritis/cervicitis.

Key words: Chlamydia trachomatis, Ureaplasma urealyticum, Urethritis, Cervicitis, Moxifloxacin