中华皮肤科杂志 ›› 2014, Vol. 47 ›› Issue (3): 163-165.

• 论著 • 上一篇    下一篇

徽章样真皮树突细胞错构瘤三例

胡瑾1,方凯2,马东来3   

  1. 1. 首都儿科研究所附属儿童医院
    2. 中国医学科学院、北京协和医学院北京协和医院
    3. 中国医学科学院、北京协和医学院北京协和医院皮肤科
  • 收稿日期:2013-05-07 修回日期:2013-10-18 发布日期:2014-03-01
  • 通讯作者: 马东来 E-mail:mdonglai@sohu.com

Medallion-like dermal dendrocyte hamartoma: three case reports

  • Received:2013-05-07 Revised:2013-10-18 Published:2014-03-01
  • Contact: Dong-Lai MA E-mail:mdonglai@sohu.com

摘要: 【摘要】 报道3例徽章样真皮树突细胞错构瘤。2例男性,1例女性,年龄2 ~ 38岁。3例患者均表现为先天发生的徽章样轻度萎缩斑,随身体按比例长大,边界清楚,表面有明显扩张的静脉,无自觉症状。3例患者均有相似的组织病理改变,表现为表皮萎缩,真皮有梭形细胞增生。这些增生的梭形细胞CD34、?育a因子和波形蛋白阳性,而S100、CD68、CD1a、CD31和平滑肌肌动蛋白均阴性。3例患者均未予特殊治疗,随访观察3 ~ 4年,皮损仅随身体略有长大。

关键词: 徽章样真皮树突细胞错构瘤, 病理过程, 皮肤表现

Abstract: Hu Jin*, Fang Kai, Ma Donglai. *Department of Dermatology, Affiliated Hospital of Children, Capital Institute of Pediatrics, Beijing 100020, China Corresponding author: Ma Donglai, Email: mdonglai@sohu.com 【Abstract】 Three cases of medallion-like dermal dendrocyte hamartoma are reported. The patients included two men and one woman, and were aged from 2 to 38 years. All the patients presented with medallion-shaped, well-defined, slightly atrophic and asymptomatic congenital patches with prominently dilated superficial veins that had grown proportionately with the body length. Histological examination revealed similar changes in all of these patients, including epidermal atrophy and dermal proliferation of spindle cells, which stained positive for CD34, factor ?育a and vimentin, but negative for S100, CD68, CD1a, CD31 and smooth muscle actin (SMA). None of the patients received special therapy, and the lesions enlarged slightly with body growth within 3 - 4 years of follow-up after the diagnosis.

Key words: Medallion-like dermal dendrocyte hamartoma, Pathologic process, Skin manifestations

引用本文

胡瑾 方凯 马东来. 徽章样真皮树突细胞错构瘤三例[J]. 中华皮肤科杂志, 2014,47(3):163-165. doi: