中华皮肤科杂志 ›› 1987, Vol. 20 ›› Issue (6): 340-342.

• • 上一篇    下一篇

红斑狼疮血清中DNA研究的初步报告

许德清, 钟幸福, 李伯有, 陈惠霞   

  1. 中山医科大学孙逸仙纪念医院皮肤科
  • 收稿日期:1986-10-03 修回日期:1987-01-22 出版日期:1987-12-15 发布日期:1987-12-15
  • 基金资助:
    中国自然科学基金会资助课题

Determination of serum levels of DNA in patients with lupus erythematosus

Xu Deqing   

  • Received:1986-10-03 Revised:1987-01-22 Online:1987-12-15 Published:1987-12-15

PDF (PC)

212

赞

摘要： 本文用二苯胺法检测了红斑狼疮患者血清中DNA(抗原)的含量,与健康人做对照,表明LE病人血清中的DNA(43.5μg/ml)高于正常人(33.4μg/ml),与病情有一定关系.DNA的检测研究可能对LE的发病机制有重要意义.

Abstract: In this study, the serum levels of DNA in the patients with lupus erythematosus are determined by diphenylamine method and compared with those of the healthy subjects. The results showed that the serum levels of DNA (43.5μg/ml) in the patients with LE were higher than those in the healthy subjects (33.4μg/ml). The levels of serum DNA in patients of LE seem to be correlated with the activity of the disease. The determinations of serum DNA are considered to be of value in studying the pathogenesis of LE.