中华皮肤科杂志 ›› 1987, Vol. 20 ›› Issue (3): 141-144.

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SLE患者尿抗核抗体组分的测定及其临床意义的探讨

施守义1, 冯树芳1, 侯爱琴1, 王勇雄2, 徐三荣2   

  1. 1. 上海医科大学皮肤病学教研室;
    2. 上海医科大学内科学教研室
  • 收稿日期:1986-04-25 修回日期:1986-10-07 发布日期:1987-06-15

Determination of urinary antinuclear antibody and its clinical sigificance in SLE

shi shouyi1   

  • Received:1986-04-25 Revised:1986-10-07 Published:1987-06-15

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摘要： 本文从46例狼疮性肾病有大量蛋白尿和7例SLE无肾病和蛋白尿患者中进行血尿ANA及其组分ds-DNA抗体、Sm抗体和nRNP抗体的检测.结果肾病组血阳性率ANA 63%>ds-DNA抗体50>nRNP抗体37%>Sm抗体22.7%,尿阳性率nRNP抗体15.2%>ANA 13%>dsDNA抗体12.5%>Sm抗体6.8%,无肾病组阳性率血ANA100% >n-RNP抗体71.4>Sm抗体28.6%,尿只n-RNP抗体阳性14.3%.尿ANA组分阳性病例除1例外,余全在大量蛋白尿患者中检出.同时亦有一定量的IgG和IgA排出,血C3值降低和CIC值增高.肾穿刺13例,ANA组分排出以膜型中最多,其次为膜增殖型和系膜增殖型.作者对SLE患者尿ANA组分检测的意义进行了阐明,最后指出从尿检出的重要性.

Abstract: This paper presents the determination of antinuclear antibodies and its specificities as ds-DNA antibodies, Sm antibodies and n-RNP antibodies of both blood and urine in 46 cases of lupus nephritis with heavy proteinuria and 7 cases of SLE without proteinuria. In the former group, the positive rate of blood was ANA 63%>ds-DNA antibodies 50%> n_RNP antibodies 37%>Sm antibodies 22.7%.

引用本文

施守义, 冯树芳, 侯爱琴, 王勇雄, 徐三荣. SLE患者尿抗核抗体组分的测定及其临床意义的探讨[J]. 中华皮肤科杂志, 1987,20(3):141-144. doi:

shi shouyi. Determination of urinary antinuclear antibody and its clinical sigificance in SLE[J]. Chinese Journal of Dermatology, 1987, 20(3): 141-144.doi: