中华皮肤科杂志 ›› 1988, Vol. 21 ›› Issue (3): 152-154.

• 论著 • 上一篇    下一篇

41例天疱疮病理及临床观察

周光霁, 张保如, 贲雅信, 王洪琛   

  1. 北京协和医院皮肤科
  • 收稿日期:1987-02-09 修回日期:1987-06-08 出版日期:1988-06-15 发布日期:1988-06-15

CLINICAL AND PATHOLOGIC OBSERVATION ON 41 PATHENTS WITH PEMPHIGUS

Zhou Guangji, Zhang Baoru   

  1. The Peking Union Medcial College Hospital, Beijing
  • Received:1987-02-09 Revised:1987-06-08 Online:1988-06-15 Published:1988-06-15

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摘要： 本文报告41例天疱疮的回顾性组织病理检查和一些病例的免疫学检查结果.在我们的41例中,21例的临床型别诊断和病理型别诊断不符合,只有24例其表皮松解或疱是在表皮的标准部位,其它17例则不在各型天疱疮的特定区.甚至在同一切片中有二型的表现,从免疫病理的检查结果看,各型天疱疮的表皮细胞间IgG的沉着均是全表皮层.我们的意见是在临床工作上不必要过分强调型别诊断.我们的全部患者病情轻,无一例是严重进行性的,一般每日给强的松40~60mg,即能很快见效并能获得临床缓解,严重副作用的病例很少,经短期追查无死亡病例.我们建议在我国天疱疮的治疗上不必要用高剂量的皮质类固醇激素.

Abstract: The results of the clinical and histopathologic. studies of 41 cases of pemphigucs are presented. Of 41 cases, 12 cases were pemphigus vulgaris, 27 cases were pemphigus erytiiematosus, and 2 cases were pemphigus foliaceus. The conditions of all cases were mild, and cone of them severe and progressive. In generzl the clinical remission might be obtained to prednisone with a dosage of 40~60 mg per day. The serious side effects were rare.