中华皮肤科杂志 ›› 1988, Vol. 21 ›› Issue (3): 148-149.

• 论著 • 上一篇    下一篇

结缔组织病免疫复合物酶联法研究

陈泽仪1, 周爱华2, 倪华妹1, Mark Clark Patricia3, Pilia Sterling3, K.Ainsworth3   

  1. 1. 上海第二医科大学附属瑞金医院免疫室;
    2. 上海市传染病医院临床实验室;
    3. 美国South Carolina医科大学
  • 收稿日期:1987-01-18 修回日期:1987-09-09 出版日期:1988-06-15 发布日期:1988-06-15

DETECTION OF IMMUNE COMPLEXES WITH A NEW IMMUNOSORBENT ASSAY IN CONNECTIVE TISSUE DISEASES

Chen Zeyi1, Zhou Aihau2   

  1. Rui-Jin Hospital, Shanghai Second Medical University
  • Received:1987-01-18 Revised:1987-09-09 Online:1988-06-15 Published:1988-06-15

摘要: 本文用酶联法以及传统的聚乙二醇(PEG)法检测177例结缔组织病(SLE129例,硬皮病36例,皮肌炎12例)和65名健康人的循环免疫复合物.SLE阳性率酶联法为82%,PEG法阳性率仅为44%.正常人酶联法阳性率3%,PEG法阳性率则高达6%.SLE酶联法的CIC均值比正常高4倍,而PEG法则高2倍.结果表明,酶联法在SLE的CIC检测中是一种较为敏感的方法.

Abstract: A new enzyme-linked immunosorbent assay (ELISA) and the classical PEG method used for detecting the circulating immune complexes (CIC) in 177 patients with connective tissue diseases (129 cases with SLE, 36 scleroderma, 12 dermatomyositis) and 65 normai controls.