中华皮肤科杂志 ›› 1988, Vol. 21 ›› Issue (3): 142-144.

• 论著 • 上一篇    下一篇

31例晕痣的临床分析及光电镜观察

赵德明1, 崔连生1, 张生德1, 黄福林2   

  1. 1. 南京铁道医学院附院皮肤科;
    2. 南京部队总医院电镜室
  • 收稿日期:1987-03-24 修回日期:1987-06-08 出版日期:1988-06-15 发布日期:1988-06-15

CLINICAL ANALYSIS, LIGHT AND ELECTRON MICROSCOPIC OBSERVATION OF 31 PATIENTS WITH HALO NEVUS

Zhao Deming1, Cui Lianshan1   

  1. The Affiliated Hospital, Nanjing Railway Medical College
  • Received:1987-03-24 Revised:1987-06-08 Online:1988-06-15 Published:1988-06-15

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摘要： 本文对31例晕痣的临床资料进行了分析,并作了7例光镜和4例电镜观察.结果表明:31例晕痣患者中伴发白癜风14例(45.1%).晕痣痣细胞周围有密集的淋巴细胞浸润.痣细胞有受损,最后则消失.晕痣的皮肤内郎格罕细胞增多.晕部表皮中黑素细胞消失.结果提示:晕痣的组织学特征符合免疫学改变.此外,本文实验还观察到晕痣组织中一种较为特殊的细胞,推测可能是郎格罕细胞在皮肤内行有丝分裂.

Abstract: The clinical data of 31 cases of halo nevus were analysed. The biopsy specimens of 7 cases were examined under light microscopy and 4 of them under electron microscopy. Of 31 patients with halo nevus 14 (45.1%) associated with vitiligo. Usually there was a dense lymphocytic infiltration around or between the nevus cells of halo nevus. Nevus cells often showed evidence of damage and destruction, and disappeared ultimately. The number of Langerhans cells seemed to be increased in the skin involved by halo nevus and the melanocytes absent in the epidermisobserved under electron microscopy.