中华皮肤科杂志 ›› 1986, Vol. 19 ›› Issue (4): 201-202.

• 论著 • 上一篇    下一篇

40例皮肤孢子丝菌病临床病理对比观察

章青, 韩国柱, 张俊达, 梅亚宁, 吴绍熙, 孔庆英, 张月苓, 是元甫, 桑红桂, 刘季和   

  1. 中国医学科学院皮肤病研究所
  • 收稿日期:1985-11-15 修回日期:1986-04-01 出版日期:1986-08-15 发布日期:1986-08-15

Sporotrichosis：A clinico-pathological analysis of 40 cases

Zhang Qing   

  • Received:1985-11-15 Revised:1986-04-01 Online:1986-08-15 Published:1986-08-15

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摘要： 本文对40例皮肤孢子丝菌病作了临床与病理的观察与分析.作者强调病损部位脓液或组织液涂片,PAS染色直接镜检有助于诊断.所查9例均可找到圆形,卵圆形或芽生孢子,但未见雪茄烟状孢子.组织病理学观察可见4种病变,混合细胞性及化脓性肉芽肿最常见,而所谓“三带”病变仅在2例见到.组织切片经淀粉酶消化后,PAS染色40例中32例为阳性.此外尚可见到PAS阳性颗粒,根据2例电镜观察推测为抱子破坏的产物.

Abstract: In the paper, 40 cases of sporotrichosis were observed clinically and histopathologically. The authors emphasized that the direct examinations of the PAS-stained smears of pus or tissue fluid from the lesions were of help in diagnosis. Round, ovate forms or budding spores (instead of "cigar-form" spores) were found in all nine cases examined. Histopatholo-gically, four kinds of changes were recognized. Mixed-cell and purulent granulomatous inflammation were seen most commonly, while the so-called "three zones" occurred only in two cases. 32 of 40 cases were positive in PAS-stained tissue sections after careful examination of spores. Besides, PAS-positive granules or debris were found in the slides of some cases which were supposed to be the fragments of the spores after EM observation of two cases.