中华皮肤科杂志 ›› 1985, Vol. 18 ›› Issue (4): 205-207.

• 论著 • 上一篇    下一篇

恶性黑棘皮病的超微结构——扫描和透射电镜研究

林元珠1, 周学敏1, 林培泉1, 李文镇2, 刘贵生2, 赵玉珍2, 李向印2   

  1. 1. 河北医学院第四医院;
    2. 河北医学院电镜室
  • 收稿日期:1984-12-04 修回日期:1985-03-15 出版日期:1985-12-15 发布日期:1985-12-15

Observation on acanthosis nigricans by SEM and TEM

Lin Yuanzhu1   

  • Received:1984-12-04 Revised:1985-03-15 Online:1985-12-15 Published:1985-12-15

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摘要： 我们利用扫描和透射电镜观察了3例恶性黑棘皮病.在扫描电镜下,角质细胞排列不规则、向上翻转和部分重备在切面上观察到表皮呈乳头状并呈现过度角化状态.在透射电镜下看到黑索细胞的树枝状突起内有大量3期和4期黑素体.在真皮的吞噬细胞内可见成堆颗粒.高倍镜看出是黑素体和次级溶酶体.这些观察表明,黑棘皮病的各称具有超微结构的证据.

Abstract: Ultrastructure changes of the skin lesions in three cases of malignant acantliosis aigricans were observed by SEM and TEM. Under SEM, the horap cells were irrgularly arranged in upturn and partially overlapped. On section tliere were papillomatosis and hyperkeratosis in the epidermis. Under TEM there were a large number of melanosomes, mainly stage Ⅲ and Ⅳ, is the dentritic processes of melonocytes. In the cytoplasm of phagocytes, many granules were observed, which were melanosomes or prelysosomes. These observations suggest that acanthosis aigricans has evidence of ultrastructural change.