中华皮肤科杂志 ›› 1985, Vol. 18 ›› Issue (1): 17-18.

• 论著 • 上一篇    下一篇

疥疮表皮郎格罕氏细胞的光镜和电镜观察

朱文元1, 王乘鹤1, 王博珍1, 夏明玉2   

  1. 1. 南京医学院附一院皮肤科;
    2. 南京医学院电镜室
  • 收稿日期:1983-09-01 修回日期:1983-12-13 出版日期:1985-03-15 发布日期:1985-03-15

Observation on epidermal Langerhans cell in scabies by ATPase staining and TEM

Zhu Wenyuan1   

  • Received:1983-09-01 Revised:1983-12-13 Online:1985-03-15 Published:1985-03-15

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摘要： 我们用ATP酶染色和透射电子显微镜观察6例疥疮患者的丘疹表皮内郎格罕细胞(LCs).其中4例LCs密度明显降低,有灶性集聚现象,许多LCs的树枝突缩短、减少或消失.3例用透射电子显微镜进行了观察,2例Birbeck颗粒形态异常,1例Birbeck颗粒增多.我们认为LCs在疥疮的免疫病理中起着重要作用.

Abstract: Egidermal Langerhans cells(LCs)from sin patients with scabies were studied with both ATPase staining,and transmission electron microscopy (TEM). The densitp of LCs was found to have decreased markedly and their distribution showed local aggregations in four cases. The dendrites of maap LCs looked shorter in length, decreased in number or totally disappeared. The shape of Birbeck granule was abnormal is two of the three cases observed with TEM. But in the other case, its number was increased. It is thought that LCs may play an important role in the immunopathology of scabies.